The Connection Between Blood Type and Autoimmune Disease

Image courtesy of Medical News Today.

Medical researchers have long asked the question: Is there a connection between one’s blood type and autoimmune disease?

Clinical studies have had varied results, mostly due to the small sample sizes of each study. Though this area needs more research, this blog post will cover some of the research that has been published so far.

Study: Rheumatic Diseases and ABO Blood Types

A 2017 study in Turkey sought to find a link between particular blood types and the incidence of rheumatic disease. Rheumatic disease includes over 200 conditions that cause pain in your joints, connective tissue, tendons, and cartilage; many of these conditions are autoimmune diseases such as rheumatoid arthritis, Sjogren’s Syndrome, and systemic lupus erythematosus.

The researchers assessed 823 patients, with the following distribution of blood types: 42.5% patients had type A blood, 33.2% had type O blood, 15.4% had type B, and 8.9% had type AB. Each patient in the study had at least one of the following nine rheumatic diseases:

  • Behçet’s disease
  • Familial Mediterranean fever (FMF)
  • Rheumatoid arthritis (RA)
  • Spondyloarthropathy
  • Systemic lupus erythematosus (SLE)
  • Systemic sclerosis (SSc)
  • Sjogren’s syndrome (SjS)
  • Undifferentiated connective tissue disease
  • Vasculitis

Their study found that there was a significant difference in the distribution of blood types among those with rheumatic diseases. The most common autoimmune diseases among those with type A blood were: rheumatoid arthritis, spondyloarthropathy, vasculitis, Behçet’s disease, and undifferentiated connective tissue disease.

The most common autoimmune diseases among those with type O blood were: systemic lupus erythematosus, systemic sclerosis, and Sjogren’s syndrome. The researchers also noted that SLE, SSc and SjS are the connective tissue disorders frequently observed with antinuclear antibodies (ANA). The rheumatic disease familial Mediterranean fever was also found to be most common in those with type O blood.

Those with blood type AB were observed to be the least likely to suffer from rheumatic disease. However, it should be noted that type AB blood is also the most rare blood type in general, and represented the smallest amount of patients studied.

In addition, it was found that there was a significant difference in the distribution of Rh factor in rheumatic diseases. Of those with rheumatic diseases, 92.2% patients were Rh positive and only 7.8% patients were Rh negative. However, it should once again be noted that a positive Rhesus Factor (Rh+) is also more common among the general population than a negative Rhesus Factor (Rh-).

Is there a link between autoimmune disease and blood type?

So, if you have blood types A or O, does this mean you are more likely to get an autoimmune disease? The researchers who conducted this study concluded: “…we believe that the higher incidence of different rheumatic diseases in different blood types is associated with different genetic predispositions.”

In other words, since blood type is inherited (i.e. genetic), the results of the study point to a likely connection between certain genes and the increased predisposition for developing an autoimmune or rheumatic disease.

Do you know your blood type?

I, for one, do not know my own blood type. This is somewhat ironic, since I’ve undergone many blood tests as part of my Sjogren’s syndrome diagnosis, as well as for monitoring my liver enzyme levels while taking certain medications to control my autoimmune symptoms.

I actually did ask my primary care doctor what my blood type was the last time he ordered a test, and he advised that finding out your blood type is not a common part of the blood testing routine, and thus, he didn’t know what mine was.

If you have an autoimmune disease (or multiple diseases), and you know your blood type, comment below and let us know, are your condition and blood type consistent with the results of this study?

Top 5 Must-Have Products for Dry Mouth | Sjogren’s Syndrome Series

Living with dry mouth can cause an array of complications. Image courtesy of Orthodontic Excellence.

As many of my subscribers know, I have an autoimmune disease called Sjogren’s Syndrome. One of the main symptoms of Sjogren’s is dry mouth, also known as xerostomia.

While those with adequate saliva levels may not think that this is a big deal, us dry mouth sufferers know that even a small amount of mouth dryness can wreck havoc on your health. According to the Mayo Clinic, mouth dryness can cause an array of health issues, including mouth sores (ulcers), oral thrush (a yeast infection in your mouth), increased dental decay, tooth loss, gum disease, bad breath, issues with chewing, swallowing and speech, loss of taste, and poor nutrition and digestion.

In fact, one of the reasons I first got diagnosed with Sjogren’s Syndrome was because of my mouth dryness. I had gone to the dentist, and I was told that I had eight cavities (yes, eight!) when I had never had a single cavity in the entire 20 years of my life. Not only that, but I had a thick coating of white gunk of my tongue (yuck!), and my dentist told me that I had oral thrush. I had to take prescription antibacterial mouthwash to get rid of the yeast infection in my mouth. Finally, I was having issues with talking and swallowing food, especially if it was dry food, like crackers or chips. I was drinking loads of water each night, but nothing seemed to alleviate my thirst.

After I was diagnosed with Sjogren’s, I understood that mouth dryness was a large part of living with this chronic autoimmune disease. I was prescribed pilocarpine (the generic for Salagen) to help stimulate saliva production. However, it took an array of dry mouth solutions to help alleviate my mouth dryness. Here are my top 5 products that I would recommend for other dry mouth suffers, below.

1. Alcohol-Free Mouthwash

My first recommendation would be to switch to using an alcohol-free mouthwash. If you suffer from dry mouth, you probably know just how drying alcohol can be. Also, if you have a dry mouth, you are likely extra sensitive to how harsh an alcohol-based mouthwash is.

My go-to mouthwash is Biotene’s Dry Mouth Oral Rinse. It helps to keep bad breath from dry mouth at bay, and helps my mouth feel more moisturized after I’ve brushed my teeth and rinsed with it. It sounds strange, but I’ve found that I sleep better at night when my mouth doesn’t feel so dry. Plus, it keeps me from having to get up in the middle of the night to drink gallons of water!

Biotene Oral Rinse Mouthwash for Dry Mouth, Breath Freshener and Dry Mouth Treatment, Fresh Mint – 33.8 fl oz

2. XyliMelts

XyliMelts are kind of like cough drops, since they’re hard discs that you can suck on to stimulate saliva production, alleviate dry mouth, and freshen your breath. Unlike cough drops, however, they’re sugar-free (they contain xylitol), so they won’t cause dental decay, which is important for dry mouth sufferers.

Since there isn’t any chewing involved (unlike gum), they easily melt in my mouth, providing me with long-lasting dryness relief. Before I started working from home, I found that these were great to take into the office and keep in my desk drawer, so I wasn’t having to chug water all the time!

Xylimelts – Mint 40 Ct

3. Moisturizing Mouth Gel

The next must-have dry mouth product on my list would be a moisturizing mouth gel. A moisturizing mouth gel is basically a saliva replacement, that you can squirt into your dry mouth to make it feel more comfortable.

Though it doesn’t have the exact same texture as real saliva, and lacks the enzymes found in it (which aid digestion), I have found that using a saliva replacement helps me sleep through the night without having to wake up to constantly drink more water. It also makes wearing my night guard/retainer at night more comfortable. Plus, it can help during the daytime if I’m having a particularly bad day, in which my mouth dryness is affecting my speech and making my voice hoarse.

Again, my go-to product comes from the brand Biotene: the Biotene Dry Mouth Oral Balance Gel. I find it is the most saliva-like among the different brands I’ve tried (the first brand I tried had the texture of toothpaste!)

3 Pack Biotene Oral Balance Dry Mouth Moisturizing Gel 1.5 oz soothe oral tissues long

4. Electric Toothbrush

If you suffer from dry mouth, a regular toothbrush just won’t make the cut. In addition to frequently visiting your dentist and dental hygienist for regular check-ups and cleanings, it’s important to take steps in your own oral hygiene routine to prevent dental caries (teeth cavities) from developing.

I’ve used several different tooth brushes over the years, and my top two would be from Oral B and Philips. These high-powered electric toothbrushes give me a deep clean, and prevent plaque from building up on my teeth and my gums from developing gingivitis. So, if you’re using a manual toothbrush still, it’s time to upgrade to some better technology.

Philips Sonicare, HX687721 ProtectiveClean 6100 Rechargeable Electric Toothbrush, White, 1 Count

Oral-B Smart 1500 Electric Power Rechargeable Battery Toothbrush, Blue

5. Chapstick for Dry Lips

If you have severe dry mouth, you’ll know that sometimes your lips can get extremely dry too, even to the point where they crack at the corners and bleed! I also have a skin condition called eczema (oh, joy!) which further contributes to dryness and skin peeling around my mouth/lip area. That’s why I regularly use chapstick to keep my lips feeling moisturized and healthy.

My favorite natural chapstick brand has got to be Burt’s Bees. It’s made out of real beeswax, rather than synthetic chemicals (like the ones found in most lipsticks), which can dry out your lips even more. Plus, they come in lots of great flavors, like coconut and pear, vanilla bean and strawberry, so your lips will never be bored!

Burt’s Bees 100% Natural Origin Moisturizing Lip Balm, Multipack with Beeswax & Fruit Extracts, 4 Tubes

These five dry mouth products have made a big difference in improving my quality of life with Sjogren’s Syndrome. Though everyone has a different regimen that works best for them, I truly hope that this blog post helps you find dry mouth solutions that work for you. And let us know in the comments below: what dry mouth products do you use to help alleviate your dryness symptoms?

Remember, always talk to your doctor before beginning a new medication, regimen, or treatment plan. Please read Autoimmune Warrior’s product recommendations disclaimer on our About Us page regarding our participation in Amazon’s Associates Program.

Carrie Ann Inaba Takes Leave of Absence Due to Autoimmune Diseases

Carrie Ann Inaba has said that she is taking a leave of absence from her TV hosting role to focus on her health.

Carrie Ann Inaba, TV host on CBS’ The Talk and judge on ABC’s hit show Dancing with the Stars opened up about her struggle living with autoimmune diseases and chronic illnesses on her blog, Carrie Ann Conversations.

The Emmy award-nominated TV personality said that she has been diagnosed with several different autoimmune diseases and chronic conditions over the years, including Sjogren’s Syndrome, Systemic Lupus Erythematosus (SLE) and Rheumatoid Arthritis (RA), and she also has the markers for Antiphospholipid Syndrome (APS), which causes blood clots. The 53-year-old dancer and choreographer says she also struggles with fibromyalgia and spinal stenosis.

As a result of her various autoimmune conditions, Inaba has taken a leave of absence from her role on The Talk so that she can focus on her health, reports MedPage Today.

Talking about her health journey, Inaba said: “Even if we are fortunate enough to get a diagnosis, we can quickly end up with more questions than answers. Often when it comes to autoimmune conditions there is no perfect solution or clear path forward.”

Inaba continued, explaining: “Coping with autoimmune conditions can sometimes feel quite lonely. When I first got diagnosed, some encouraged me to keep my struggles to myself, but I’ve found that it’s always been better to be honest about my needs and realities than to stay silent. I believe strongly in sharing my journey, my solutions, and the things that have helped me.”

In this spirit, Inaba has shared on her blog the products that have helped her cope with her autoimmune disease symptoms – including eye dryness, mouth dryness, joint pain, fatigue, brain fog and more – so that others can benefit from these products and see if they work for them.

This isn’t the first time that Carrie Ann Inaba has opened up about her health struggles. The starlet previously posted on Instagram about how she felt ashamed of her autoimmune diseases, and wanting “…to be what people see. And people see a healthy person, from the outside.” However, confronting her health problems made Inaba reflect on who she is as a person, besides just her identity as a “sexy dancer chick.”

From all of us at Autoimmune Warrior, we want to thank Carrie Ann for opening up about her health journey as an #AutoimmuneWarrior, and raising awareness about the 80+ autoimmune diseases affecting over 23 million Americans. Because of celebrities like her, more people among the general population are learning about autoimmune conditions, and why extensive research is needed to find better treatments, and eventually, a cure.